Perilla frutescens, is a member of the Lamiaceae/Labiatae family and commonly called perilla. Perilla is produced by many countries including China, India, Japan, Korea, Thailand, other East Asian countries. The herb is about 1 m high with small flowers, a gray-brown fruit, and glossy, downy-haired leaves. Cultivation of the crop is grown from seed and sown in May. Harvesting is usually between the end of September and beginning of October. The applicable parts of perilla plants are the leaves and seeds. There are two main types: red and green perilla. Perilla seeds, also called EBARA seed. Perilla oil is a light yellow clear and transparent liquid, with aromatic odor and slightly soluble in alcohol. Perilla seed oil is used in cooking oil and as a fuel.
Compared to other plant oils, perilla seed oil contains the highest proportion of omega-3 (ALA) fatty acids (54–64%). The omega-6 (linoleic acid) component is approximately 14% and omega-9 (Oleic acid) is also present in perilla oil. These polyunsaturated fatty acids (PUFA) possess various health benefits and may prevent many diseases like cardiovascular disorders, cancer, inflammatory diseases, rheumatoid arthritis and other conditions.
Omega 3 are polyunsaturated fatty acids including:
EPA: Eicosa Pentaenoic Acid
DHA: Docosa Hexaenoic Acid
ALA: Alpha Lenolenic Acid
Fish oil contains both DHA & EPA
Vegetable oils contain ALA
ALA is metabolized in the body to EPA & DHA
Possible Health Benefits of Omega 3
Improve Depression & Anxiety
Promote Healthy Vision
Promote Healthy Brain Development During Conception
Decrease Risk Factors of Cardiovascular Disease
Improve ADHD symptoms
Improve Metabolic Syndrome
Improve Autoimmune Disorders
Improve Mental Disorders
Improve Dementia & Alzheimer’s Disease
Improve Childhood Asthma
Reduce Fat accumulation in Liver
Improve Joint & Bone Health
Decrease Menstrual Pain
Promote Healthy Sleep
Promote Healthy Skin
Omega 6 FFA are classified as essential fatty acids which may promote healthy brain function, development and growth. The body cannot make them and they need to be obtained from dietary sources and supplements. Omega 6 FFA include:
Gamma – Linolenic Acid (GLA)
Dihomo-Gamma-Linolenic Acid (DGLA)
Linoleic acid is converted in the body to Gamma – Linolenic Acid (GLA)
GLA is then converted to Dihomo-Gamma-Linolenic Acid (DGLA)
GLA reduces inflammation
DGLA fights inflammation
The conversion of GLA to DGLA is stimulated by Mg, Zn, vitamin C, vitamin B3 and vitamin B6
Possible Health Benefits of Omega 6
Maintain Healthy Skin
Stimulate Hair Growth
Maintain Reproductive System
May improve various disorders including: Diabetic neuropathy, rheumatoid arthritis, allergies, ADHD, eczema, hypertension, menopausal symptoms, breast pain, multiple sclerosis, osteoporosis, PMS, diabetes
Omega 6 FFA are classified as non-essential fatty acids since the body can make them from unsaturated fat. They include:
Possible Health Benefits of Omega 9
Lower Cholesterol Levels
Boost Immune System
May Prevent Cancer
Advantages of Perilla Oil
Perilla oil is a balanced natural formula of Omega 3, 6 and 9
It is highest in Omega, lowest in Omega 9 and intermediate in Omega 6
No Fishy Smell
No Fishy Taste
No GI Upset
No Heavy Metals
Safe for people who have fish allergy
Can Omega 6 FFA increase the risk of heart diseases?
In the human body Omega 3 and Omega 6 compete with each other for incorporation into cell membranes and this may lead to various responses including:
Modulation of Membrane Protein Function
If Omega 6 FFA predominate and are incorporated in cell membranes more than Omega 3, this may lead to the formation of pro-inflammatory metabolites which cause inflammation. The most serious consequence is the inflammation which causes damage in the lining of arteries and increases the risk of cardiovascular disorders. Pro-inflammatory metabolites include:
Prostaglandins (PGI2 & PGE2)
If Omega 3 FFA predominate and are incorporated in cell membranes more than Omega 6, this may lead to the formation of anti-inflammatory metabolites which prevent inflammation. Anti-inflammatory metabolites include:
Prostaglandins (PGI3 & PGE3)
The American Heart Association (AHA) considers Omega 6 is safe if it is 5 – 10% of the total daily calories. Other studies confirmed the lower the ratio of Omega 6 to Omega 3, the better. The acceptable safe ratio of Omega 6 to Omega 3 is 3:1.
Ratio of Omega 6 to Omega 3 in Vegetable Oils
Perrila Oil 1:5
Cotton seed 234:1
Perilla Oil possesses the Best Ratio of Omega 6:Omega 3 FA compared to other vegetable oils
A review article (2011) entitled “Health effects of omega-3,6,9 fatty acids: Perilla frutescens is a good example of plant oils” published in Oriental Pharmacy and Experimental Medicine concluded:
Yet if we increase our intake of omega-3 fatty acids, we may prevent the formation of these inflammatory substances and actually increase the production of anti-inflammatory substances.
Most important to people concerned about cardiovascular disease, omega 3 fatty acids have been shown to improve blood pressure and vascular resistance, lower triglycerides, prevent abnormal heart rhythm and sudden cardiac death, and may reduce the risk of heart attack.
The high content of omega-3 fatty acids, the absence of mercury risk from fish sources, and the beneficial effects of perilla oil is the best supplement to achieve balance in these valuable fatty acids.
Although perilla has been around for centuries, is has recently as a viable vegetarian omega-3 alternative for nutrition and health.
Linolenic acid is also a precursor of a special group of prostaglandins.
Person, those who are vegetarian or dislike the taste of fish, have a fish allergy or are just unable to tolerate fish oil due to reflux, vegetarian sources (Perilla oil) of omega-3 fatty acids are preferable.
Plant based omega-3s including perilla, flax, purslane, and walnut will provide essential fats for necessity of our body.
Now that the low fat diet craze is over, healthy fats from sources such as perilla oil, fish oils, flaxseed oil, hemp oil, and evening primrose oil are making their way back into the diets.
More clinical evidence is required before recommendations can be made for any clinical usage of perilla.
A research study (2000) entitled “Effects of perilla seed oil supplementation on leukotriene generation by leucocytes in patients with asthma associated with lipometabolism published in International Archives of Allergy and Immunology concluded “Dietary supplementation with perilla seed oil in selected patients with asthma suppresses the generation of LTC4 and is associated with clinical features such as respiratory function and lipometabolism”.
A research study (1999) entitled “Long-term effects of dietary alpha-linolenic acid from perilla oil on serum fatty acids composition and on the risk factors of coronary heart disease in Japanese elderly subjects” published in Journal of Nutritional Science and Vitaminology concluded “These data indicate that, even in elderly subjects, a 3 g/d increase of dietary ALA could increase serum EPA and DHA in 10 mo without any major adverse effects”.
A recent research study (2016) entitled “Anti-atherosclerotic effects of perilla oil in rabbits fed a high-cholesterol diet” published in Laboratory Animal Research concluded “The results indicate that perilla oil prevents atherosclerosis and fatty liver by controlling lipid metabolism, and that it could be the first choice oil to improve diet-induced metabolic syndrome”.
A research study (2013) entitled “Effects of perilla oil on plasma concentrations of cardioprotective (n-3) fatty acids and lipid profiles in mice” published in Nutrition Research and Practice concluded “In summary, perilla oil, a native product of Korea, currently used as a raw material for delicacies like bibimbab, increased cardioprotective DPA and EPA contents in the plasma of mice. Accordingly, it is possible that perilla oil can substitute for fish oil or imported flaxseed oil as an alternative cardioprotective vegetable oil. Finally, conduct of further studies will be necessary in order to elucidate the effects of perilla oil on plasma DHA and EPA concentrations in humans.”.
A research study (2014) entitled “Perilla oil improves blood flow through inhibition of platelet aggregation and thrombus formation” published in Laboratory Animal Research concluded “The results indicate that perilla oil inhibit platelet aggregation by blocking thromboxane formation, and thereby delay thrombosis following oxidative arterial wall injury. Therefore, it is proposed that perilla oil could be a good candidate without adverse effects for the improvement of blood flow”.
A research study (1997) entitled “Perilla oil prevents the excessive growth of visceral adipose tissue in rats by down-regulating adipocyte differentiation” published in The Journal of Nutrition concluded “These results suggest that perilla oil or (n-3) PUFA prevents excessive growth of adipose tissue in rats at least in part by suppressing the late phase of adipocyte differentiation”.
Fine’s Omega Complete Pectin Gummies
Perilla oil is the main ingredient of Fine’s Omega Complete Pectin Gummies for Kids. This product contains a balanced, vegetarian, safe and effective formula of Omega 3,6,9 fatty acids which promotes children’s overall health by:
Enhancing brain function
Promoting normal growth & development
Reducing risks of stroke and heart diseases.
Decreasing cholesterol levels
Boosting the immune system
Minimizing risks of infections